Not say it is short term or problematic but getting equipments such as skimmer,FR is difficult for these all in one tank... As it limited in space and you will have problem sourcing your equipment and if they can fit in the compartment, they will be hanging so it will be not very nice, it is better to have a sump and place everything inside much neater too..
And those all in one tank trap heat easily as it is covered and sometimes the fans just do not work as well and the lighting is pretty much fixed... It is more of the limitation that it gives you problems..