find it take quite a few safety considerations so use UV instead for me.
1) My skimmer can only take 50mg so cannot buy bigger size
2) need to take care and use ozone friendly material for all connection like tubing and connectors
3) recommend to go through carbon before going back to main tank.
4) best to use orp controller before overdose > 450
5) I see most reef keepers don't use it maybe due to the feeding
6) if something wrong you can actually smell it and dangerous